Author

Ting Shen

Primary ORCID profile (0000-0002-3937-4427 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Ting SheniD1 paper · University of Hong Kong

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:rat· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Chen Ding· 2 shared Gang Wei· 2 shared Guoliang Lv· 2 shared Hongbo Nie· 2 shared Jinfeng Hu· 2 shared Jun GuiD· 2 shared Meng Chen· 2 shared Miao Han· 2 shared

Activity by Year

2015-2015 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Chen Ding

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2 papers

Recent·Most cited

Global lengthening of 3′ untranslated regions of mRNAs by alternative cleavage and polyadenylation in cellular senescence

Miao Han, Guoliang Lv, Hongbo Nie, Ting Shen, Yichi Niu, Xueping Li, Meng Chen, Xia Zheng, Wei Li, Chen Ding, Gang Wei, Jun Gu, Xiao-Li Tian, Yufang Zheng, Xinhua Liu, , Ting Ni

This study shows that alternative polyadenylation (APA) leads to longer 3' UTRs in senescent cells, affecting gene regulation through miRNA and RBP binding sites.

bioRxiv · Dec 2, 2015 · PreprintGenomics

Progressive lengthening of 3′ untranslated regions of mRNAs by alternative cleavage and polyadenylation in cellular senescence of mouse embryonic fibroblasts

Miao Han, Guoliang Lv, Hongbo Nie, Ting Shen, Yichi Niu, Xueping Li, Meng Chen, Xia Zheng, Wei Li, Chen Ding, Gang Wei, Jun Gu, Xiao-Li Tian, Yufang Zheng, Xinhua Liu, , Ting Ni

The paper investigates APA regulation in cellular senescence, finding genes in senescent cells preferentially use distal polyadenylation sites, associated with longer 3′ UTRs and senescence-related pathways.

bioRxiv · Nov 11, 2015 · PreprintGenomics