Interactions between calmodulin and neurogranin govern the dynamics of CaMKII as a leaky integrator
Mariam Ordyan, Tom Bartol, Mary B. Kennedy, Padmini Rangamani, Terrence J. Sejnowski A B
This paper uses rule-based modeling to show that neurogranin modulates CaMKII phosphorylation dynamics, acting as a leaky integrator of calcium signals through interactions with calmodulin and phosphatase.
PLoS Computational Biology · Jul 17, 2020Peer-reviewedNeuroscience