Author
California Institute of TechnologyORCID 0000-0003-1369-0525Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Saahil Acharya, Taka A. Tsunoyama, Christian Hoffmann…·Akihiro Kusumi
This study shows SynGAP forms condensates at low concentrations and recruits PSD95 and receptor oligomers, suggesting it initiates PSD formation.
Thomas M. Bartol, Mariam Ordyan, Terrence J. Sejnowski A B…·Mary B. Kennedy
The paper develops a spatial model of CaMKII autophosphorylation in synaptic spines to show that CaM-trapping prolongs phospho-CaMKII lifetime by hindering dephosphorylation.
Anjalika Chongtham, Jose Mario Isas, NITIN KUMAR PANDEY…·Ali Khoshnan
This study shows sonicated HTTex1 fibrils selectively seed neurons, leading to toxic assemblies and neuronal damage.
Mariam Ordyan, Tom Bartol, Mary B. Kennedy…·Terrence J. Sejnowski A B
This paper uses rule-based modeling to show that neurogranin modulates CaMKII phosphorylation dynamics, acting as a leaky integrator of calcium signals through interactions with calmodulin and phosphatase.
Matthew C Pharris, Neal M. Patel, Tyler G. VanDyk…·Tamara L. Kinzer‐Ursem
The paper develops a rule-based computational model of CaMKII holoenzyme to explore how Ca2+/CaM binding stabilizes autophosphorylation and regulates synaptic plasticity.
Tara L Mastro, Anthony R. Preza, Shinjini Basu…·Mary B. Kennedy
The paper shows that synGAP heterozygosity leads to increased TARP levels in the PSD of female rodents but not males, indicating a sex difference in PSD adaptation.