Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
Julie C. Worrell, Kerrie E Hargrave, George E. Finney, Chris A. H. Hansell, John J Cole, Jagtar Singh Nijjar, Fraser R. Morton, Marieke Pingen, Tom Purnell, Kathleen A. J. Mitchelson, Euan Brennan, Clíodhna M. Daly, Jay Allan, Georgios Ilia, Vanessa Herder, , Megan K. L. MacLeod
The paper shows that lung structural cells retain an inflammatory imprint after influenza infection, enabling faster viral control upon re-challenge.
Nature Communications · Aug 1, 2025Peer-reviewedImmunology