Author

Tom Soare

insitro, inc. (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:GWAS summary statistics· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Daphne KolleriD· 2 shared Theofanis KaraletsosiD· 2 shared Aaron TopoliD· 1 shared Ahmed Sandakli· 1 shared Aidan H. McMorrowiD· 1 shared Ajamete KaykasiD· 1 shared Angela Oliveira PiscoiD· 1 shared Anna Merkoulovitch· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Daphne KollerORCID

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Author profile →

2 papers

Recent·Most cited

Deep Learning Analysis on Images of iPSC-derived Motor Neurons Carrying fALS-genetics Reveals Disease-Relevant Phenotypes

Rahul Atmaramani, Tommaso Dreossi, Kevin Ford, Lin Gan, Jana M. Mitchell, Shengjiang Tu, Jeevaa Velayutham, Haoyang Zeng, Michael Chickering, Tom Soare, Srinivasan Sivanandan, Ryan Conrad, Yujia Bao, Santiago Akle, Jonathan Liu, , Samuel Sances

The paper uses deep learning on images of iPSC-derived motor neurons with fALS mutations to identify disease-relevant phenotypes and molecular differences.

bioRxiv · Jan 4, 2024 · PreprintNeuroscience

EmbedGEM: A framework to evaluate the utility of embeddings for genetic discovery

Sumit Mukherjee, Zachary Ryan McCaw, Jingwen Pei, Anna Merkoulovitch, Tom Soare, Raghav Tandon, David Amar, Hari Somineni, Christoph Klein, Santhosh Satapati, David Lloyd, Christopher S. Probert, Daphne Koller, Colm T. O’Dushlaine, Theofanis Karaletsos

EmbedGEM evaluates embeddings for genetic discovery by assessing heritability and disease relevance using polygenic risk scores and genome-wide association statistics.

Bioinformatics Advances · Jan 1, 2024Peer-reviewedBioinformatics