Jonathan Liu

This study uses single-cell RNA sequencing to show that M. tuberculosis ESX-1 promotes the recruitment and differentiation of anti-inflammatory macrophages in infected mouse lungs.

The paper identifies 22 molecularly distinct neuronal subtypes in the lateral septum by profiling transcriptional identity and examines their connectivity, morphology, and electrophysiology.

This study uses single-cell transcriptomics and proteomics to analyze Vaccinia virus infection dynamics and host response heterogeneity in HeLa and fibroblast cells.

The paper uses deep learning on images of iPSC-derived motor neurons with fALS mutations to identify disease-relevant phenotypes and molecular differences.

The paper shows that intrinsic developmental origins and local signals shape septal astrocyte identity through distinct molecular and morphological features in medial and lateral septal nuclei.

The paper compares MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing in mouse liver and kidney, finding MERFISH provides comparable results and robust cell type identification without needing integration with scRNA-seq atlases.