Author

Shengjiang Tu

Howard Hughes Medical InstituteORCID 0000-0003-3616-3242Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aaron TopoliD· 1 shared Ahmed Sandakli· 1 shared Aidan H. McMorrowiD· 1 shared Ajamete KaykasiD· 1 shared Alexander PolyzosiD· 1 shared Angela Oliveira PiscoiD· 1 shared Aristotelis TsirigosiD· 1 shared Bhishma Amlani· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Aaron TopolORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 4, 2024

Deep Learning Analysis on Images of iPSC-derived Motor Neurons Carrying fALS-genetics Reveals Disease-Relevant Phenotypes

Rahul Atmaramani, Tommaso Dreossi, Kevin Ford…·Samuel Sances

The paper uses deep learning on images of iPSC-derived motor neurons with fALS mutations to identify disease-relevant phenotypes and molecular differences.

11 citations

humanimaging

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJun 18, 2019

Context-dependent requirement of H3K9 methyltransferase activity during cellular reprogramming to iPSCs

Simon E. Vidal, Alexander Polyzos, Jorge Morales-Valencia…·Matthias Stadtfeld

This study shows that reducing EHMT1/2 activity during reprogramming with ascorbic acid impairs iPSC formation and viability, highlighting the role of H3K9 methylation in reprogramming efficiency.

1 citation

mouseDNA methylation

𝕏 PostBluesky