DNA aptamers to interfere with HasA, the hemophore of the heme assimilation system in Pseudomonas aeruginosa, as a potential antimicrobial strategy
Federico Bosetto, Tongyuan Wei, Katherine M. Stott, Stephen H. McLaughlin, Laura S. Itzhaki, Maria Zacharopoulou, Ioanna Mela
This paper identifies DNA aptamers that bind the truncated form of HasA, a hemophore in Pseudomonas aeruginosa, under acidic conditions, showing potential as antimicrobial agents.
bioRxiv · Sep 5, 2026 · PreprintBiophysics