Quantifying small GTPase activation status using a novel fluorescence HPLC-based assay
Makoto Araki, Yukika Kasuya, Kaho Yoshimoto, Toshiaki Katada, Kenji Kontani
This paper introduces a fluorescence HPLC-based assay to quantify small GTPase activation states, demonstrating its application in analyzing RHEB and KRAS in cells and tumor models.
Journal of Biological Chemistry · Apr 24, 2025Peer-reviewedCell Biology