Author

Tri Nguyen

Deakin UniversityPrimary ORCID profile (0000-0001-9936-1794 · 12 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Tri NguyeniD12 papers · Harvard University

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1 Organism:human· 1

Frequent Co-Authors

Anshul Bharat KundajeiD· 1 shared Arun PadmanabhaniD· 1 shared Axel ViseliD· 1 shared Casey A. GiffordiD· 1 shared Chad J. MungeriD· 1 shared Charu BalamuruganiD· 1 shared Chloe V. McCreeryiD· 1 shared Danila BredikhiniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Anshul Bharat KundajeORCID

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2 papers

Recent·Most cited

Interpreting variants associated with congenital heart disease with a regulatory map of the human fetal heart

X. Rosa Ma, Stephanie D. Conley, Maggie S. Chen, Michael Kosicki, Yifan Lu, Danila Bredikhin, Ran Cui, Maya U. Sheth, Wei‐Lin Qiu, Dulguun Amgalan, Sijie Chen, Robin M. Perelli, Neil Slaven, Michael T. Montgomery, Sarah Fan Xia, , J Engreitz

This study creates a gene regulation map of the human fetal heart to interpret genetic variants associated with congenital heart disease and cardiac traits, identifying valvular interstitial cells as key regulators.

medRxiv · Nov 20, 2024 · PreprintGenetic & Genomic Medicine

GraphDTA: Predicting drug-target binding affinity with graph neural networks

Thin Nguyen, Hang Le, Thomas P. Quinn, Tri Nguyen, Thuc Duy Le, Svetha Venkatesh

Representing drugs as molecular graphs, GraphDTA lowers drug-target affinity prediction error to MSE 0.229 on Davis and 0.139 on Kiba versus deep learning baselines.

Bioinformatics · Oct 15, 2020Peer-reviewedBioinformatics✦ In-depth digest