Herpes Simplex Virus Assembly and Spread in murine skin after infection from the outside
Timmy Richardo, Xiaokun Liu, Katinka Döhner, Tsung-Yu Chao, Anna Buch, Anne Binz, Anja Pohlmann, Madeleine de le Roi, Wolfgang Baumgärtner, Korbinian Brand, Rudolf Bauerfeind, Reinhold Förster, Beate Sodeik, Stephan Halle
This paper develops a novel murine ex vivo skin explant model to study HSV-1 infection and spread in intact skin, showing HSV-1 exclusively spreads in the epidermis through infected keratinocytes.
Journal of Virology · Feb 13, 2025Peer-reviewedMicrobiology