Author

Tuula Rantasalo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Approach:experimental assay· 3 Assay:whole-genome sequencing· 3 Assay:DNA methylation· 2 Research Focus:variant calling· 2 Research Focus:database / resource· 1 Research Focus:sequence-to-function modeling· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Juha-Pekka PursiheimoiD· 3 shared Manu V. TammineniD· 3 shared Nea LaineiD· 3 shared Tatu HirvoneniD· 3 shared Anna Musku· 2 shared Anttoni KorkiakoskiiD· 2 shared Jorma KimiD· 2 shared Jukka LaineiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Juha-Pekka PursiheimoORCID

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Author profile →

3 papers

Recent·Most cited

Application of the Nicking Loop™ targeted library preparation method to DNBSEQ™ sequencing

Simona Adamusová, Anttoni Korkiakoski, Tatu Hirvonen, Hui Ren, Nea Laine, Anna Musku, Tuula Rantasalo, Jorma Kim, Juuso Blomster, Jukka Laine, Chongjun Xu, Manu V. Tamminen, Juha-Pekka Pursiheimo

This paper demonstrates that the Nicking Loop targeted library preparation method works well with the DNBSEQ sequencing platform, matching performance of linear libraries on Illumina.

bioRxiv · Mar 12, 2026 · PreprintMolecular Biology

Evaluation of ensilication technology for ambient DNA preservation

Michael Blas, Celeste Yu, Farnoosh Abbas Aghababazadeh, Vanessa Hoelscher, Marcus Volz, Linden L. Morales, Kaytee Jarolik, Xiuhua Dong, Sheila M. Dobin, Tuula Rantasalo, Tatu Hirvonen, Juha-Pekka Pursiheimo, Nea Laine, Nils Homer, Cassandra Chamoun, , Philippe Lucien Bedard

This paper evaluates ensilication technology for ambient DNA preservation, finding it maintains sequencing fidelity and reduces artifacts compared to frozen storage.

NAR Molecular Medicine · Jan 1, 2026Peer-reviewedGenetic & Genomic Medicine

Nicking Loop™: An infinite amplification of single-stranded circular DNA

Simona Adamusová, Nea Laine, Anttoni Korkiakoski, Tatu Hirvonen, Anna Musku, Tuula Rantasalo, Jorma Kim, Juuso Blomster, Jukka Laine, Manu V. Tamminen, Juha-Pekka Pursiheimo

The paper introduces Nicking Loop, a method for converting DNA into circular single-stranded DNA for NGS, showing improved reproducibility, sensitivity, and compatibility with sequencing platforms.

bioRxiv · May 8, 2025 · PreprintMolecular Biology