GM-CSF orchestrates monocyte and granulocyte responses to Cryptococcus gattii
Alison Ricafrente, Sreemoyee Acharya, Shuyi Chen, Adiza Abass, Aelita Arshakyan, Tyler Olson, Apurwa Trivedi, Lena J. Heung
This study shows GM-CSF promotes harmful immune responses to C. gattii by facilitating macrophage and eosinophil activity while blocking neutrophil entry, leading to increased fungal burden and lung damage.
PLoS Pathogens · Apr 7, 2026Peer-reviewedImmunology