Lena J. Heung

This study identifies TREM2 as a DAP12-associated receptor that inhibits macrophage antifungal responses to Cryptococcus neoformans by reducing fungal uptake and M1 polarization.

This study shows GM-CSF promotes harmful immune responses to C. gattii by facilitating macrophage and eosinophil activity while blocking neutrophil entry, leading to increased fungal burden and lung damage.

The paper identifies an IFN-STAT1-CYBB axis that mediates protective crosstalk between plasmacytoid dendritic cells and neutrophils during Aspergillus fumigatus infection.