A mitochondrial redox switch licenses the onset of morphogenesis in animals
Updip Kahlon, Francesco Dalla Ricca, Saraswathi Jayarajan Pillai, Marine Olivetta, Kevin M. Tharp, Li-En Jao, Omaya Dudin, Kent L. McDonald, Mustafa G. Aydogan
The paper identifies a mitochondrial redox switch that licenses the onset of morphogenesis in embryos by showing that mitochondrial superoxide production is critical for this transition.
bioRxiv · Oct 28, 2024 · PreprintDevelopmental Biology