Author

Uri Z. Miles

Georgia Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew C. McShaniD· 1 shared Daizheng Tu· 1 shared Danny D. SahtoeiD· 1 shared Finn Snow· 1 shared Georg MeisliD· 1 shared Hannah L. HaniD· 1 shared Heike LamaniD· 1 shared Jiapeng WeiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Andrew C. McShanORCID

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1 paper

Recent·Most cited

State-selective inhibition of alpha-synuclein aggregation by de novo oligomer-binding proteins

Yunxuan Zhang, Hannah L. Han, Lei Ortigosa-Pascual, Uri Z. Miles, Jiapeng Wei, Lexie E. Berkowicz, Finn Snow, Daizheng Tu, Georg Meisl, Shrutika Sansaria, Timothy J. Nott, Heike Laman, Randal Halfmann, Andrew C. McShan, Danny D. Sahtoe, Tuomas P. J. Knowles

This study designs de novo proteins that selectively inhibit alpha-synuclein aggregation by targeting specific intermediates, with one binder preferentially inhibiting oligomer formation and secondary nucleation.

bioRxiv · Sep 25, 2026 · PreprintBiophysics