Author

V. A. Adalsteinsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. D. D'Andrea· 1 shared A. G. Waks· 1 shared B. Kochupurakkal· 1 shared C. E. Dunn· 1 shared D. Kim· 1 shared D. Shea· 1 shared E. Nguyen· 1 shared E. P. Winer· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. D. D'Andrea

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Author profile →

2 papers

Recent·Most cited

CODEC enables 'single duplex' sequencing

J. H. Bae, R. Liu, E. Nguyen, J. Rhoades, T. Blewett, K. Xiong, D. Shea, G. Gydush, S. Tabrizi, Z. An, S. Patel, G. M. Makrigiorgos, T. R. Golub, V. A. Adalsteinsson

CODEC improves mutation detection by combining NGS throughput with single-molecule resolution, achieving similar accuracy with fewer reads.

bioRxiv · Jun 11, 2021Bioengineering

Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer

A. G. Waks, O. Cohen, B. Kochupurakkal, D. Kim, C. E. Dunn, J. Buendia Buendia, S. Wander, K. Helvie, M. R. Lloyd, L. Marini, M. E. Hughes, S. S. Freeman, S. P. Ivy, J. Geradts, S. Isakoff, , N. Wagle

This study identifies genomic reversion and increased DNA end resection as mechanisms of resistance to PARP inhibitors and platinum in BRCA1/2-mutant metastatic breast cancer, with RAD51 foci as a potential biomarker.

bioRxiv · Nov 10, 2019Cancer Biology