Author

V. A. Bohr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. Croteau· 2 shared M. Okur· 2 shared B. D. Sahbaz· 1 shared D. L. Croteau· 1 shared E. F. Fang· 1 shared E. Fivenson· 1 shared J. Patel· 1 shared J. Tian· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

D. Croteau

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Author profile →

3 papers

Recent·Most cited

Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice

M. Okur, R. Kimura, B. D. Sahbaz, U. Manor, J. Patel, L. Andrade, K. Puligilla, D. Croteau, V. A. Bohr

This study shows that long-term NR supplementation prevents age-related hearing loss in mice by restoring NAD+ levels and modulating synaptic and lipid pathways.

bioRxiv · Aug 25, 2022Animal Behavior & Cognition

Self-assembly of multi-component mitochondrial nucleoids via phase separation

M. Feric, T. G. Demarest, J. Tian, D. L. Croteau, V. A. Bohr, T. Misteli

This study shows that mitochondrial nucleoids assemble via phase separation, with TFAM and mtDNA forming viscoelastic droplets, and links this process to mitochondrial dysfunction in HGPS.

bioRxiv · Jul 20, 2020Cell Biology

Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling

M. Okur, E. F. Fang, E. Fivenson, V. Tiwari, D. Croteau, V. A. Bohr

This study shows that Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis via NAD+ signaling, with NAD+ supplementation improving lifespan and healthspan in CS nematodes.

bioRxiv · Mar 1, 2020Cell Biology