Author

L. Andrade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Animal Behavior & Cognition· 1 Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

U. Manor· 2 shared A. Biswas· 1 shared A. C. Parra· 1 shared A. Malhotra· 1 shared A. N. Engelman· 1 shared A. T. Alhinho· 1 shared A. Tammaro· 1 shared B. D. Sahbaz· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

U. Manor

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding

T. Jing, Z. Shan, T. Dinh, A. Biswas, S. Jang, J. Greenwood, M. Li, Z. Zhang, G. Gray, H. J. Shin, B. Zhou, D. Passos, T. S. Strutzenberg, S. Aiyer, L. Andrade, , D. Lyumkis

This study determines cryo-EM structures of HIV-1 integrase tetramers and intasome hexadecamers, revealing structural plasticity and functional roles in viral integration and RNA binding.

bioRxiv · Jan 26, 2024 · PreprintBiochemistry

Air Pollution Aggravates Renal Ischemia-Reperfusion-Induced Acute Kidney Injury

T. R. Sanches, A. C. Parra, P. Sun, M. Graner, L. Y. U. Itto, L. Butter, N. Claessen, J. J. T. H. Roelofs, S. Florquin, M. M. Veras, M. d. F. Andrade, P. H. N. Saldiva, J. Kers, L. Andrade, A. Tammaro

This study shows that PM2.5 exposure worsens IRI-induced AKI in mice by increasing tubular damage, immune activation, and fibrosis markers.

bioRxiv · Aug 17, 2023 · PreprintPathology

Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice

M. Okur, R. Kimura, B. D. Sahbaz, U. Manor, J. Patel, L. Andrade, K. Puligilla, D. Croteau, V. A. Bohr

This study shows that long-term NR supplementation prevents age-related hearing loss in mice by restoring NAD+ levels and modulating synaptic and lipid pathways.

bioRxiv · Aug 25, 2022Animal Behavior & Cognition

SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2

Y. Lei, J. Zhang, C. R. Schiavon, M. He, L. Chen, H. Shen, Y. Zhang, Q. Yin, Y. Cho, L. Andrade, G. S. Shadel, M. Hepokoski, T. Lei, H. Wang, J. Zhang, , J. Y.-J. Shyy

This study shows SARS-CoV-2 Spike protein damages endothelial cells by reducing ACE2 expression and impairing mitochondrial function, leading to vascular inflammation.

bioRxiv · Dec 4, 2020Pathology

Unisexual flower initiation in the monoecious Quercus suber L., a molecular approach

R. S. Sobral, H. G. Silva, S. C. C. Laranjeira, J. Magalhaes, L. Andrade, A. T. Alhinho, M. M. R. Costa

The paper identifies genetic mechanisms controlling unisexual flower initiation in Quercus suber by analyzing floral regulatory gene homologs and their expression patterns.

bioRxiv · Feb 13, 2020Plant Biology