Author

E. F. Fang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Y. Aman· 2 shared A. Bugai· 1 shared A. F. Arutyunyan· 1 shared A. H. Lystad· 1 shared A. Ianevski· 1 shared A. L. Zhuze· 1 shared A. Simonsen· 1 shared A. Waage· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Y. Aman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CD8+ T cell epitope variations suggest a potential antigen presentation deficiency for spike protein of SARS-CoV-2

C. Qiu, C. Xiao, Z. Wang, G. Zhu, X. Chen, L. Gao, J. Den, J. Su, H. Su, E. F. Fang, Z. Zhang, J. Zhang, O. J. Luo, P. Wang, G. Chen

The paper identifies HLA-A2 restricted T cell epitopes in SARS-CoV-2 spike protein and finds that variations in these epitopes may reduce T cell activation and contribute to immune escape.

bioRxiv · Jan 22, 2021 · PreprintImmunology

GAK and PRKCD are positive regulators of PRKN-independent mitophagy

M. J. Munson, B. J. Mathai, L. Trachsel, M. Yoke Wui Ng, L. Rodriguez de la Ballina, S. Schultz, Y. Aman, A. H. Lystad, S. Singh, S. Singh, J. Wesche, E. F. Fang, A. Simonsen

This study identifies GAK and PRKCD as positive regulators of PRKN-independent mitophagy through genetic screening and functional analysis in vitro and in vivo.

bioRxiv · Nov 5, 2020Cell Biology

Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling

M. Okur, E. F. Fang, E. Fivenson, V. Tiwari, D. Croteau, V. A. Bohr

This study shows that Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis via NAD+ signaling, with NAD+ supplementation improving lifespan and healthspan in CS nematodes.

bioRxiv · Mar 1, 2020Cell Biology

Chemical, physical and biological triggers of Bcl-xL-mediated apoptosis

A. Ianevski, E. Kulesskiy, K. Krpina, G. Lou, Y. Aman, A. Bugai, K. Aasumets, Y. Akimov, D. Bulanova, K. Gildemann, A. F. Arutyunyan, O. Y. Susova, A. L. Zhuze, P. Ji, W. Wang, , D. E. Kainov

This study shows that Bcl-xL-specific inhibitors, when combined with DNA-damaging agents or physical insults, trigger apoptosis in various cell types and C. elegans by releasing Bad and Bax from Bcl-xL.

bioRxiv · Jan 13, 2020Cancer Biology