Sustained antibody response to ZIKV infection induced by NS1 protein is accompanied by the progressive appearance of autoreactive antibodies and cross-reactive B cell clones.
C. B. Cavazzoni, V. B. Bozza, L. Tostes, B. Maia, L. Mesin, A. Schiepers, J. Ersching, R. L. Neris, J. N. Conde, D. R. Coleho, L. Conde, H. A. Paula-Neto, T. M. Lima, R. G. F. Alvim, L. R. Castilho, , A. M. Vale
The paper investigates the humoral immune response to Zika virus NS1, showing its immunodominance and association with autoreactive and cross-reactive B cell clones.
bioRxiv · Dec 24, 2020Immunology