Expanding Targeted Instrumentation for Discovery Applications: Complement Reporter Ion Quantification with a Quadrupole-Ion Trap Instrument
Edward R. Cruz, Alex N. T. Johnson, V. B. Pujari, Qi Zhang, Thao Nguyen, Michael Stadlmeier, Jessica Wang, Cristina C. Jacob, Graeme C. McAlister, Philip M. Remes, Martin Wühr
This paper demonstrates that a quadrupole-ion trap instrument can perform multiplexed shotgun proteomics with accuracy comparable to a dedicated tribrid instrument, offering a cost-effective alternative.
Journal of Proteome Research · Aug 6, 2025Peer-reviewedSystems Biology