Mitoxantrone modulates a glycosaminoglycan-spike complex to inhibit SARS-CoV-2 infection
Q. Zhang, P. Radvak, J. Lee, Y. Xu, V. Cao-Dao, M. Xu, W. Zheng, C. Z. Chen, H. Xie, Y. Ye
This study shows Mitoxantrone inhibits SARS-CoV-2 infection by targeting the spike-GAG complex, but also affects nucleosome dynamics.
bioRxiv · Oct 15, 2021 · PreprintCell Biology