The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis
V. Deruelle, S. Bouillot, V. Job, E. Taillebourg, M.-O. Fauvarque, I. Attree, P. Huber
The paper identifies DNAJC5 as a host chaperone required for ExoU-mediated necrosis in Pseudomonas aeruginosa.
bioRxiv · Nov 4, 2020Microbiology