Author

V. H. Bustos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bispo· 1 shared A. Jedlicki· 1 shared A. Lam· 1 shared A. Sinha· 1 shared E. Chang· 1 shared E. Mui· 1 shared H. Rosenthal· 1 shared M. Flajolet· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Bispo

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1 paper

Recent·Most cited

Rational development of a small-molecule activator of CK1γ2 that decreases C99 and beta-amyloid levels

V. H. Bustos, Y. K. Sunkari, A. Sinha, M. Pulina, A. Bispo, M. Hopkins, A. Lam, S. F. Kriegsman, E. Mui, E. Chang, A. Jedlicki, H. Rosenthal, M. Flajolet, P. Greengard, S. Sinha

This study identifies CK1γ2 as a therapeutic target for Alzheimer's disease by showing its activation reduces C99 and beta-amyloid levels through increased PS1-Ser367 phosphorylation.

bioRxiv · Apr 28, 2023Pharmacology & Toxicology