Cancer BiologybioRxiv
Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer
V. H. Cruz, E. N. Arner, W. Du…·R. A. Brekken
This study identifies TBK1 as a key driver of epithelial plasticity in KRAS-mutant pancreatic cancer, showing its role in tumor growth and metastasis through Axl-mediated activation.
DOI 10.1172/jci.insight.126117