TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1
A. P. Carreca, V. M. Pravata, G. Murphy, H. Nagase, L. Troeberg, S. D. Scilabra
This study identifies MMP-1 as a new LRP-1 ligand and shows TIMP-3 enhances its binding to LRP-1, promoting scavenging of MMP-1.
bioRxiv · Dec 23, 2019Biochemistry