Author

V. Male

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Assay:flow cytometry· 2 Organism:mouse· 2

Frequent Co-Authors

A. O. Cuff· 4 shared E. V. Woon· 2 shared M. R. Johnson· 2 shared S. Dertschnig· 2 shared A. Hall· 1 shared B. Browne· 1 shared D. Nikolaou· 1 shared E. M. Whettlock· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersImmunology

A. O. Cuff

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4 papers

Recent·Most cited

Uterine NK cells underexpress receptors recognizing HLA-C2 and HLA-G in reproductive failure

E. V. Woon, D. Nikolaou, K. MacLaran, J. Norman-Taylor, P. Bhagwat, A. O. Cuff, M. R. Johnson, V. Male

This study examines uNK subsets in women with reproductive failure and finds reduced receptor expression and function, suggesting impaired interaction with EVT during early pregnancy.

bioRxiv · Nov 25, 2022Immunology

Dynamic changes in uterine NK cell subset frequency and function over the menstrual cycle and pregnancy

E. M. Whettlock, E. V. Woon, A. O. Cuff, B. Browne, M. R. Johnson, V. Male

This study investigates how uterine NK cell subsets change in frequency and function across the menstrual cycle and pregnancy using scRNAseq and flow cytometry data.

bioRxiv · Feb 21, 2022Immunology

Tbet promotes NK cell egress from the bone marrow and CXCR6 expression in immature NK cells

A. O. Cuff, T. Perchet, S. Dertschnig, R. Golub, V. Male

The paper shows Tbet promotes NK cell egress from bone marrow by enhancing CXCR6 expression and coordinating migration.

bioRxiv · Nov 19, 2019Immunology

TGFβ in the obese liver mediates conversion of NK cells to a less cytotoxic ILC1-like phenotype

A. O. Cuff, F. Sillito, S. Dertschnig, A. Hall, T. Luong, R. Chakraverty, V. Male

This study shows that TGFβ in obese livers converts NK cells to a less cytotoxic ILC1-like phenotype, which may protect against NAFLD but increase cancer risk.

bioRxiv · Jul 18, 2019Immunology