Supramolecular complexes of GCAP1: towards the development of effective biologics for inherited retinal dystrophies
A. Biasi, V. Marino, G. Dal Cortivo, D. Dell'Orco
This paper investigates how the E111V mutation in GCAP1 affects dimerization and GC1 activity, showing that RD3 can partially restore cGMP production in mutated variants.
bioRxiv · Mar 7, 2024 · PreprintBiochemistry