Author

N. Anderson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 3 Evolutionary Biology· 2 Bioinformatics· 1 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:whole-genome sequencing· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2

Frequent Co-Authors

A. Gilbert· 2 shared A. Waters· 2 shared C. Hirsch· 2 shared D. Eickholt· 2 shared J. Renk· 2 shared M. Yandeau-Nelson· 2 shared S. Flint-Garcia· 2 shared T. Hattery· 2 shared

Activity by Year

2020-2022 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersPlant Biology

A. Gilbert

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Author profile →

9 papers

Recent·Most cited

Clinically-relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance

A. Manas, K. Aaltonen, N. Anderson, K. Hansson, A. Adamska, A. Seger, H. Yasui, H. van den Bos, K. Radke, J. Esfandyari, M. S. Bhave, J. Karlsson, D. C. J. Spierings, F. Foijer, D. Gisselsson, D. Bexell

The paper applies a clinically-relevant chemotherapy regimen to neuroblastoma PDX models to identify transcriptional patterns and mechanisms of chemoresistance.

bioRxiv · Apr 1, 2022Cancer Biology

Proteolytic Activation of Human-specific Olduvai Domains by the Furin Protease

A. Pacheco, A. Issaian, J. Davis, N. Anderson, T. Nemkov, B. Vögeli, K. Hansen, J. Sikela

The paper shows human-specific Olduvai domains are cleaved by furin protease, suggesting they function as proproteins activated by this processing, linking their expansion to human brain evolution.

bioRxiv · Jul 6, 2021Evolutionary Biology

Predicting Moisture Content During Maize Nixtamalization Using Machine Learning with NIR Spectroscopy

M. Burns, J. Renk, D. Eickholt, A. Gilbert, T. Hattery, M. Holmes, N. Anderson, A. Waters, S. Kalambur, S. Flint-Garcia, M. Yandeau-Nelson, G. Annor, C. Hirsch

This study uses machine learning with NIR spectroscopy to predict maize kernel moisture content during nixtamalization, finding environmental factors and complex genetics influence the trait.

bioRxiv · May 19, 2021Plant Biology

Genetic Architecture of Kernel Compositional Variation in a Maize Diversity Panel

J. Renk, A. Gilbert, T. Hattery, C. O'Connor, P. Monnahan, N. Anderson, A. Waters, D. Eickholt, S. Flint-Garcia, M. Yandeau-Nelson, C. Hirsch

This study identifies genetic loci associated with compositional traits in maize using GWAS, revealing significant genetic and environmental influences on grain quality.

bioRxiv · Mar 29, 2021Plant Biology

Divergent epigenetic profiles from two differentially impacted wild populationsof estuarine cordgrass (Sporobolus alterniflorus)

L. DeCarlo, F. Meckler, M. Hans, S. Kelemen, H. Magun, M. Noah, L. Pappajohn, N. Anderson, R. Berger, J. Berkel, N. Brooke, L. Chen, O. Chijioke, N. Dewees, P. Faulkner, , R. Cox

This study examines how two populations of estuarine cordgrass show opposite DNA methylation patterns under heat stress, suggesting epigenetic mechanisms may enable rapid adaptation to urban environmental challenges.

bioRxiv · Mar 22, 2021 · PreprintPlant Biology

Genomic Evidence of Environmental and Resident Salmonella Senftenberg and Montevideo Contamination in the Pistachio Supply-chain

J. Haendiges, G. Davidson, J. Pettengill, E. Reed, T. Blessington, J. D. Miller, N. Anderson, S. Myoda, E. Brown, J. Zheng, R. V. Tikekar, M. Hoffmann

This study analyzes Salmonella contamination in pistachios using genomic data to identify persistent strains and their adaptation mechanisms.

bioRxiv · Mar 18, 2021Microbiology

Gene-rich X chromosomes implicate intragenomic conflict in the evolution of bizarre genetic systems

N. Anderson, K. S. Jaron, C. N. Hodson, M. B. Couger, J. Sevcik, B. Weinstein, S. Pirro, L. Ross, S. W. Roy

The paper investigates the role of X chromosome gene richness in the evolution of genetic systems with paternal genome elimination, finding increased X linkage in species with such systems.

bioRxiv · Oct 4, 2020Evolutionary Biology

mtDNA replication in dysfunctional mitochondria promotes deleterious heteroplasmy via the UPRmt

Q. Yang, P. Liu, N. Anderson, T. Shpilka, Y. Du, N. Uma Naresh, K. Luk, J. Lavelle, R. Zeinert, P. Chien, S. Wolfe, C. Haynes

The paper shows ATFS-1 promotes {Delta}mtDNA replication by recruiting POLG, while LONP-1 inhibition increases wildtype mtDNA binding and improves heteroplasmy ratio and OXPHOS function.

bioRxiv · Sep 1, 2020 · PreprintCell Biology

Improving COVID-19 Testing Efficiency using Guided Agglomerative Sampling

F. Minhas, D. Grammatopoulos, L. Young, I. Amin, D. Snead, N. Anderson, A. Ben-Hur, N. Rajpoot

This paper proposes agglomerative sampling to improve testing efficiency for low-prevalence COVID-19 populations, achieving ~40% test savings in simulations.

bioRxiv · Apr 13, 2020 · PreprintBioinformatics