Author

V. Mezger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. de Thonel· 2 shared D. Saberan-Djoneidi· 2 shared A. J. Da Silva· 1 shared E. Henriksson· 1 shared J. C. Luoto· 1 shared J. Joutsen· 1 shared J.-P. Concordet· 1 shared L. Pesonen· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

A. de Thonel

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2 papers

Recent·Most cited

Gambogic acid and gambogenic acid induce a thiol-dependent heat shock response and disrupt the interaction between HSP90 and HSF1 or HSF2

L. Pesonen, S. Svartsjo, V. Back, A. de Thonel, V. Mezger, D. Saberan-Djoneidi, P. Roos-Mattjus

This study shows gambogic acid and gambogenic acid induce a thiol-dependent heat shock response by disrupting HSP90 interactions with HSF1 and HSF2, suggesting caution in their use as cancer therapeutics.

bioRxiv · Apr 26, 2021Cell Biology

HSF2 protects against proteotoxicity by maintaining cell-cell adhesion

J. Joutsen, A. J. Da Silva, M. A. Budzynski, J. C. Luoto, A. de Thonel, J.-P. Concordet, V. Mezger, D. Saberan-Djoneidi, E. Henriksson, L. Sistonen

This study shows HSF2 protects cells from proteotoxicity by maintaining cell-cell adhesion through regulation of cadherin genes.

bioRxiv · Dec 27, 2018Cell Biology