Author

L. Sistonen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

E. Henriksson· 2 shared J. C. Luoto· 2 shared A. de Thonel· 1 shared A. J. Da Silva· 1 shared D. Saberan-Djoneidi· 1 shared H. Schwartz· 1 shared H. Williams· 1 shared J. E. Eriksson· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

E. Henriksson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vivo-mimicking 3D cultures secrete distinct extracellular vesicles upon cancer cell invasion

E. Henriksson, J. C. Luoto, L. S. Coelho-Rato, S. H. Bengs, J. Roininen, J. E. Eriksson, L. Sistonen

This study shows that cancer organoids in 3D cultures secrete distinct extracellular vesicles compared to 2D cultures, with changes in EV cargo during invasion.

bioRxiv · Dec 22, 2020Cell Biology

HSF2 protects against proteotoxicity by maintaining cell-cell adhesion

J. Joutsen, A. J. Da Silva, M. A. Budzynski, J. C. Luoto, A. de Thonel, J.-P. Concordet, V. Mezger, D. Saberan-Djoneidi, E. Henriksson, L. Sistonen

This study shows HSF2 protects cells from proteotoxicity by maintaining cell-cell adhesion through regulation of cadherin genes.

bioRxiv · Dec 27, 2018Cell Biology

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation

T. Kijima, T. L. Prince, M. Tigue, K. Yim, H. Schwartz, K. Beebe, S. Lee, M. Budzynski, H. Williams, J. Trepel, L. Sistonen, S. K. Calderwood, L. Neckers

This study shows HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction, revealing a noncanonical role for HSP90 in modulating HSF1 activity by removing HSF1 trimers from DNA.

bioRxiv · Mar 2, 2018Biochemistry