Engineered nickel bioaccumulation in Escherichia coli by NikABCDE transporter and metallothionein overexpression
P. Diep, L. Shen, J. A. Wiesner, N. Mykytczuk, V. Papangelakis, A. F. Yakunin, R. Mahadevan
This study engineered Escherichia coli to enhance nickel bioaccumulation using overexpressed NikABCDE transporter and metallothionein, achieving 7-fold improvement but with reduced cell viability.
bioRxiv · Aug 26, 2022Bioengineering