Cancer BiologybioRxiv
Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming.
A. Velez-Delgado, K. L. Donahue, K. L. Brown…·M. Pasca di Magliano
This study shows that extrinsic KRAS signaling reprograms pancreatic fibroblasts to create an inflammatory microenvironment that supports tumor growth.
DOI 10.1016/j.jcmgh.2022.02.016