Author

K. L. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Plant Biology· 2 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Organism:plant (other)· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. A. Raines· 2 shared F. Bednar· 2 shared K. L. Donahue· 2 shared M. Pasca di Magliano· 2 shared N. G. Steele· 2 shared P. E. Lopez-Calcagno· 2 shared R. E. Menjivar· 2 shared S. B. Kemp· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersPlant Biology

C. A. Raines

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Notch signaling regulates immunosuppressive tumor-associated macrophage function in pancreatic cancer

W. Yan, N. G. Steele, S. B. Kemp, R. E. Menjivar, W. Du, E. S. Carpenter, K. L. Donahue, K. L. Brown, V. Irizarry-Negron, S. Yang, W. R. Burns, Y. Zhang, M. Pasca di Magliano, F. Bednar

This study shows Notch signaling in tumor-associated macrophages promotes immunosuppression in pancreatic cancer, and blocking it enhances immune therapy effectiveness.

bioRxiv · Jan 11, 2023Cancer Biology

Widespread exposure to SARS-CoV-2 in wildlife communities

A. R. Goldberg, K. E. Langwig, K. L. Brown, J. M. Marano, P. Rai, K. M. King, A. K. Sharp, A. Ceci, C. D. Kailing, M. J. Kailing, R. Briggs, M. G. Urbano, C. Roby, A. M. Brown, J. Weger-Lucarelli, , J. R. Hoyt

The paper documents SARS-CoV-2 exposure in six wildlife species and finds higher seroprevalence in areas with high human activity, suggesting human-to-animal transmission events.

bioRxiv · Nov 4, 2022Ecology

Rieske FeS overexpression in tobacco provides increased abundance and activity of Cytochrome b6f

E. A. Heyno, M. Ermakova, P. E. Lopez-Calcagno, R. Woodford, K. L. Brown, J. S. Matthews, C. B. Osmond, C. A. Raines, S. von Caemmerer

Overexpressing Rieske FeS in tobacco increases Cytochrome b6f abundance and activity, leading to transient improvements in photosynthetic electron transport.

bioRxiv · Jun 28, 2022Plant Biology

Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming.

A. Velez-Delgado, K. L. Donahue, K. L. Brown, W. Du, V. Irizarry-Negron, R. E. Menjivar, E. L. Lasse-Opsahl, N. G. Steele, S. The, J. Lazarus, V. R. Sirihorachai, W. Yan, S. B. Kemp, S. A. Kerk, M. Bollamplly, , M. Pasca di Magliano

This study shows that extrinsic KRAS signaling reprograms pancreatic fibroblasts to create an inflammatory microenvironment that supports tumor growth.

bioRxiv · Aug 26, 2021Cancer Biology

Latent gammaherpesvirus exacerbates arthritis and requires age-associated B cells

I. C. Mouat, Z. J. Morse, I. Shanina, K. L. Brown, M. S. Horwitz

This study shows that latent gammaherpesvirus infection worsens arthritis in mice by requiring age-associated B cells.

bioRxiv · Feb 2, 2021Immunology

Simultaneous stimulation of RuBP regeneration and electron transport increases productivity and water use efficiency under field conditions

P. E. Lopez-Calcagno, K. L. Brown, A. J. Simkin, S. J. Fisk, T. Lawson, C. A. Raines

bioRxiv · Jan 27, 2020 · PreprintPlant Biology