ImmunologybioRxiv
Host PGD2 acting on DP2 receptor attenuates Schistosoma mansoni infection-driven hepatic granulomatous fibrosis
G. N. Pezzella-Ferreira, C. R. R. Pao, I. Bellas…·C. Bandeira-Melo
This study investigates the role of PGD2 and its receptor DP2 in hepatic fibrosis caused by Schistosoma mansoni infection, finding that PGD2/DP2 signaling protects against fibrosis rather than promoting it.
DOI 10.1371/journal.ppat.1011812