Author

V. Shafirovich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

N. E. Geacintov· 2 shared A. Durandin· 1 shared A. H. Sales· 1 shared A. Kolbanovskiy· 1 shared H. Mu· 1 shared J. H. Min· 1 shared K. M. Feher· 1 shared S. Broyde· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

N. E. Geacintov

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2 papers

Recent·Most cited

Variable inhibition of unwinding rates of DNA catalyzed by the SARS-Cov-2 (COV19) helicase nsp13 by structurally distinct single DNA lesions.

A. H. Sales, S. Ciervo, T. Lupoli, V. Shafirovich, N. E. Geacintov

This study investigates how different DNA lesions affect the unwinding activity of the SARS-CoV-2 helicase nsp13, showing varying degrees of inhibition based on lesion structure.

bioRxiv · Oct 13, 2021Biochemistry

The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion.

K. M. Feher, A. Kolbanovskiy, A. Durandin, Y. Shim, J. H. Min, Y. C. Lee, V. Shafirovich, H. Mu, S. Broyde, N. E. Geacintov

This study shows that XPC-RAD23B does not bind to DNA lesions with a missing nucleotide opposite the lesion, due to structural stabilization preventing XPC binding.

bioRxiv · Sep 14, 2020Biochemistry