Author

Y. Shim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

J. H. Min· 2 shared A. Durandin· 1 shared A. Kolbanovskiy· 1 shared B. A. Garcia· 1 shared C. D. Kaplan· 1 shared H. J. Kim· 1 shared H. Mu· 1 shared K. M. Feher· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

J. H. Min

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2 papers

Recent·Most cited

Structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in Nucleotide Excision Repair

T. van Eeuwen, Y. Shim, H. J. Kim, T. Zhao, S. Basu, C. D. Kaplan, B. A. Garcia, J. H. Min, K. Murakami

The paper presents a cryo-EM structure of an NER initiation complex involving Rad4-Rad23-Rad33 and TFIIH bound to a DNA lesion, revealing DNA unwinding and translocation mechanisms.

bioRxiv · Jan 14, 2021Biophysics

The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion.

K. M. Feher, A. Kolbanovskiy, A. Durandin, Y. Shim, J. H. Min, Y. C. Lee, V. Shafirovich, H. Mu, S. Broyde, N. E. Geacintov

This study shows that XPC-RAD23B does not bind to DNA lesions with a missing nucleotide opposite the lesion, due to structural stabilization preventing XPC binding.

bioRxiv · Sep 14, 2020Biochemistry