Author

V. Sivaraman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. E. Keating· 2 shared A. Singer· 1 shared D. Whitney· 1 shared F. Rigoldi· 1 shared J. C. Halpin· 1 shared M. W. Ilunga· 1 shared R. A. Grant· 1 shared T. Hwang· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

A. E. Keating

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2 papers

Recent·Most cited

Molecular determinants of TRAF6 binding specificity suggest that native interaction partners are not optimized for affinity

J. C. Halpin, D. Whitney, F. Rigoldi, V. Sivaraman, A. Singer, A. E. Keating

The paper identifies TRAF6 MATH domain binding preferences using combinatorial peptide libraries and structural modeling, revealing that native ligands are not optimized for affinity.

bioRxiv · May 8, 2022Biochemistry

Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP proteins

T. Hwang, R. A. Grant, M. W. Ilunga, V. Sivaraman, A. E. Keating

The paper identifies how proline-rich motifs interact with ENAH EVH1 domain through sequence context, revealing extended SLiMs and their role in protein-protein interactions.

bioRxiv · Mar 22, 2021Biochemistry