The deubiquitinase Ubp3/Usp10 constrains glucose-mediated mitochondrial repression via phosphate budgeting
V. Vengayil, S. Niphadkar, S. Adhikary, S. Varahan, S. Laxman
The paper identifies Ubp3/Usp10 as a deubiquitinase that limits mitochondrial activation in high glucose by regulating phosphate availability through glycolytic flux.
bioRxiv · Dec 29, 2022Biochemistry