Membrane and glycocalyx tethering of DNA nanostructures for enhanced uptake
W. Wang, B. Chopra, V. Walawalkar, Z. Liang, R. Adams, M. Deserno, X. Ren, R. Taylor
This study enhances DNA nanostructure cellular uptake by targeting membrane and glycocalyx, showing improved uptake and endocytic pathways involving scavenger receptors and clathrin/caveolin mechanisms.
bioRxiv · Mar 9, 2023Bioengineering