R. Adams

A tale of too many trees: a conundrum for phylogenetic regression

This paper investigates the consequences of gene tree-species tree mismatch in phylogenetic regression and finds high false positive rates when trees are mismatched.

Membrane and glycocalyx tethering of DNA nanostructures for enhanced uptake

This study enhances DNA nanostructure cellular uptake by targeting membrane and glycocalyx, showing improved uptake and endocytic pathways involving scavenger receptors and clathrin/caveolin mechanisms.

Robust Phylogenetic Regression

This paper introduces robust phylogenetic regression to improve trait association tests by reducing sensitivity to model violations while maintaining statistical power.

A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters

Single-cell profiling of Ebola virus infection in vivo reveals viral and host transcriptional dynamics

This study uses single-cell transcriptomics and protein profiling to analyze EBOV infection in rhesus monkeys, revealing changes in immune cell dynamics and viral/host gene expression.

Extensive transfer of genes for edible seaweed digestion from marine to human gut bacteria

The paper shows gut bacteria have extensively adapted to digest seaweed polysaccharides through gene transfer from marine bacteria, revealing widespread metabolic plasticity in the human gut microbiome.

Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis)

This study uses CT and PET/CT imaging to quantify SARS-CoV-2-induced lung abnormalities in crab-eating macaques, providing an objective endpoint for evaluating medical countermeasures.