Cryptochrome Stabilization Ameliorates Chronic Pain
Liting Wei, Yanying Wu, Florian Zirpel, Grace Flower, J. V Vierbergen, V. Wieser, Stuart N. Peirson, Hannah Sleven, Alexandra V. Pokhilko, M. Zameel Cader
The paper identifies a peripheral molecular clock in sensory neurons that regulates diurnal pain behaviors and shows that stabilizing cryptochromes reduces pain sensitivity.
bioRxiv · Jul 15, 2022 · PreprintNeuroscience