Cell BiologybioRxiv
Cation-chloride cotransporters, Na/K pump, and channels in cell water and ions regulation: in silico and experimental studies of the U937 cells under stopping the pump and during RVD
A. A. Vereninov, V. Yurinskaya
The paper develops a computational model of ion homeostasis in U937 cells, showing that stopping the Na/K pump leads to a 'physical' RVD driven by ion gradients, not changes in membrane channels.
DOI 10.3389/fcell.2021.736488