Presenilin-deficient neurons and astrocytes display normal mitochondrial phenotypes
Sabrina Contino, Céline Vrancx, Núria Suelves, Devkee M. Vadukul, Valéry L. Payen, Serena Stanga, Luc Bertrand, Pascal Kienlen‐Campard
The paper shows that PS1 and PS2 deficiency in primary neurons and astrocytes does not cause mitochondrial dysfunction, contrasting with findings in immortalized cell lines.
Frontiers in Neuroscience · Jan 22, 2021Peer-reviewedNeuroscience