Targeting CLK1 by CRISPR tools and pharmacological inhibition modulates the innate immune response and dengue virus replication
Berta Pozzi, Agustina Magalí Lucero, Valeria Buggiano, Miguel Angel Pelaez, Cybele Garcia, Anabella Srebrow
The paper shows that CLK1 inhibition enhances antiviral defenses against dengue virus by boosting IFN-stimulated gene expression and reducing viral replication.
Biochemical Journal · Oct 12, 2026Peer-reviewedMolecular Biology