Berta Pozzi

Targeting CLK1 by CRISPR tools and pharmacological inhibition modulates the innate immune response and dengue virus replication

The paper shows that CLK1 inhibition enhances antiviral defenses against dengue virus by boosting IFN-stimulated gene expression and reducing viral replication.

Differential contribution of the RNA recognition motifs to SRSF1 protein interaction network

This study identifies the differential roles of SRSF1's RNA recognition motifs in protein interactions using SILAC proteomics.

SUMO conjugation regulates the activity of the Integrator complex

The paper shows that SUMO conjugation regulates the Integrator complex's activity through SUMOylation of INTS11, affecting its function and localization.

Influence of RNA circularity on Target RNA-Directed MicroRNA Degradation

The paper investigates whether circular or linear RNA topology affects Target RNA-Directed MicroRNA Degradation (TDMD), finding that circular RNAs can inhibit while linear forms can drive TDMD.