CRISPRi Screen Uncovers lncRNA Regulators of Human Monocyte Growth
Cristina Flores-Arenas, Eric Malekos, Christy Montano, Sergio Covarrubias, Lisa A. Sudek, Valory Dempsey, Vuky Huynh, Sol J. Katzman, Susan B Carpenter
The paper uses a CRISPRi screen to identify lncRNAs critical for human monocyte viability, finding two lncRNAs that regulate proliferation and cell cycle genes.
Journal of Biological Chemistry · May 7, 2025Peer-reviewedImmunology