The essential role of 2,4-dienoyl-CoA reductase for degradation of complex fatty acid mixtures
Veronica Schiaffi, Viola Pavoncello, Bastien Prost, Audrey Solgadi, Frédéric Barras, Emmanuelle Bouveret
This paper shows that 2,4-dienoyl-CoA reductase (FadH) is essential for E. coli to degrade unsaturated fatty acids in complex mixtures and that eukaryotic DECR enzymes can functionally replace FadH.
mBio · Oct 29, 2025Peer-reviewedMicrobiology