MIC13-linked cristae disruption causes metabolic failure and early fibrotic remodelling in mitochondrial liver disease
Alexander Becker, Thomas Oliver Eichmann, Viacheslav Vasiliev, Kira an Mey, Patrick Petzsch, Andrea Rossi, Felix Distelmaier, Ruchika Anand
This study uses patient-derived iPSCs to model a MIC13 variant causing mitochondrial liver disease, revealing metabolic defects and early fibrosis through multi-omics analysis.
Cell Death and Disease · Sep 15, 2026Peer-reviewedBiochemistry